VRTX
Vertex Pharmaceuticals·NASDAQ
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VRTX fundamentals
Vertex Pharmaceuticals (VRTX) released its earnings on Nov 3, 2025: revenue was 3.08B (YoY +11.05%), beat estimates; EPS was 4.8 (YoY +9.59%), beat estimates.
Revenue / YoY
3.08B
+11.05%
EPS / YoY
4.8
+9.59%
Report date
Nov 3, 2025
VRTX Earnings Call Summary for Q3,2025
- Revenue Growth: Q3 2025 revenue $3.08B (+11% YoY), driven by CFTR modulators, ALYFTREK, CASGEVY, and JOURNAVX.
- CF Breakthroughs: ALYFTREK covers 95% U.S. CF patients, 50%+ achieve normal sweat chloride. TRIKAFTA 1-2 year-olds show 70% sweat chloride normalization.
- Pain Innovation: JOURNAVX reduces opioid use by 90%, CASGEVY nearing $100M annual revenue.
- Kidney Pipeline: Pove (IgAN) Phase III interim analysis complete, FDA breakthrough designation granted. Inaxaplin Phase III interim analysis underway.
- Financial Strength: Non-GAAP EPS $4.80 (+10% YoY). $12B cash balance, $1.1B Q3 share buybacks.
- Strategic Expansion: Building commercial infrastructure for renal portfolio, targeting 150,000+ IgAN patients.
EPS
Revenue
Revenue & Expenses
VRTX has released its 2025 Q3 earnings report, with revenue of 3.08B, reflecting a YoY change of 10.99%, and net profit of 1.08B, showing a YoY change of 3.59%. The Sankey diagram below clearly presents VRTX's revenue sources and cost distribution.
Key Indicators
Vertex Pharmaceuticals (VRTX) key financial stats and ratios, covering profitability, financial health, and leverage.
Vertex Pharmaceuticals (VRTX)'s revenue and profit trends over recent years, visualized with a waterfall chart to showcase the revenue-to-profit funnel.
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Vertex Pharmaceuticals (VRTX)'s asset and liability trends over recent years, visualized with a waterfall chart to illustrate changes in its asset-liability structure.
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Vertex Pharmaceuticals (VRTX)'s cash flow trends over recent years, visualized with a waterfall chart to illustrate changes in its operating, investing, and financing cash flows.
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Where does Vertex Pharmaceuticals (VRTX) generate its revenue? Explore its key revenue streams and top earning regions.
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Track Vertex Pharmaceuticals (VRTX) Dividend Yield, Payout Ratio & Sustainability Through Its Dividend History
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Dividend Yield
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What is Vertex Pharmaceuticals's latest dividend and current dividend yield?What were the key takeaways from Vertex Pharmaceuticals's earnings call?What does Vertex Pharmaceuticals do and what are its main business segments?What is the revenue and EPS growth rate for Vertex Pharmaceuticals year over year?Did Vertex Pharmaceuticals beat or miss consensus estimates last quarter?What guidance did Vertex Pharmaceuticals's management provide for the next earnings period?What factors drove the changes in Vertex Pharmaceuticals's revenue and profit?What is Vertex Pharmaceuticals's gross profit margin?
