UPB
Upstream Bio·NASDAQ
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UPB fundamentals
During Q4 2025, Upstream Bio (UPB) reported revenue of 668.00K, a YoY change of 8.97%. Net income was -42.46M, a YoY change of -99.88%. Click to view the full income statement and explore the company's earnings performance.
Income Statement
Q3,2023 | Q4,2023 | Q1,2024 | Q2,2024 | Q3,2024 | Q4,2024 | Q1,2025 | Q2,2025 | Q3,2025 | Q4,2025 | TTM |
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Start Date | Jul 1, 2023 | Oct 1, 2023 | Jan 1, 2024 | Apr 1, 2024 | Jul 1, 2024 | Oct 1, 2024 | Jan 1, 2025 | Apr 1, 2025 | Jul 1, 2025 | Oct 1, 2025 | -- |
End Date | Sep 30, 2023 | Dec 31, 2023 | Mar 31, 2024 | Jun 30, 2024 | Sep 30, 2024 | Dec 31, 2024 | Mar 31, 2025 | Jun 30, 2025 | Sep 30, 2025 | Dec 31, 2025 | -- |
Fiscal Year-End | Dec 31 | Dec 31 | Dec 31 | Dec 31 | Dec 31 | Dec 31 | Dec 31 | Dec 31 | Dec 31 | Dec 31 | -- |
Revenue | 621.00K -- | 450.00K -- | 640.00K -- | 510.00K -- | 607.00K -2.25% | 613.00K +36.22% | 566.00K -11.56% | 937.00K +83.73% | 683.00K +12.52% | 668.00K +8.97% | 2.85M -- |
Sales and Services Revenue | 621.00K -- | 450.00K -- | 640.00K -- | 510.00K -- | 607.00K -2.25% | 613.00K +36.22% | 566.00K -11.56% | 937.00K +83.73% | 683.00K +12.52% | 668.00K +8.97% | 2.85M -- |
Operating Expenses | 10.01M -- | 14.78M -- | 15.65M -- | 18.05M -- | 19.50M +94.86% | 26.93M +82.21% | 32.58M +108.13% | 45.28M +150.88% | 38.52M +97.52% | 46.84M +73.91% | 163.22M -- |
Selling, General and Administrative Expenses | 2.22M -- | 3.23M -- | 3.96M -- | 3.98M -- | 4.07M +83.28% | 5.16M +59.89% | 6.78M +71.18% | 7.42M +86.36% | 5.54M +36.27% | 6.67M +29.24% | 26.41M -- |
General and Administrative Expenses | 2.22M -- | 3.23M -- | 3.96M -- | 3.98M -- | 4.07M +83.28% | 5.16M +59.89% | 6.78M +71.18% | 7.42M +86.36% | 5.54M +36.27% | 6.67M +29.24% | 26.41M -- |
Research and Development Expenses | 7.79M -- | 11.55M -- | 11.69M -- | 14.07M -- | 15.43M +98.16% | 21.77M +88.45% | 25.80M +120.66% | 37.87M +169.14% | 32.98M +113.67% | 40.17M +84.49% | 136.81M -- |
Operating Income | -9.39M -- | -14.33M -- | -15.01M -- | -17.54M -- | -18.89M -101.29% | -26.32M -83.66% | -32.01M -113.24% | -44.35M -152.83% | -37.83M -100.25% | -46.17M -75.42% | -160.36M -- |
Non-Operating Income (Loss) | 6.28M -- | 2.50M -- | 4.12M -- | 2.86M -- | 2.90M -53.84% | 5.08M +103.28% | 4.74M +15.15% | 4.38M +53.07% | 4.09M +40.85% | 3.71M -26.95% | 16.92M -- |
Gain (Loss) on Change in Fair Value | 4.77M -- | 985.00K -- | 2.86M -- | 0 -- | 0 -100.00% | 0 -100.00% | 0 -100.00% | 0 -- | 0 -- | 0 -- | -- -- |
Other Non-Operating Income (Loss) | -16.00K -- | -7.00K -- | -6.00K -- | -15.00K -- | -3.00K +81.25% | 0 +100.00% | 0 +100.00% | -50.00K -233.33% | -19.00K -533.33% | 54.00K -- | -15.00K -- |
Net Interest Expense | -1.53M -- | -1.52M -- | -1.27M -- | -2.88M -- | -2.90M -90.18% | -5.08M -234.17% | -4.74M -274.64% | -4.43M -54.01% | -4.11M -41.36% | -3.65M +28.01% | -16.93M -- |
Interest Income | 1.53M -- | 1.52M -- | 1.27M -- | 2.88M -- | 2.90M +90.18% | 5.08M +234.17% | 4.74M +274.64% | 4.43M +54.01% | 4.11M +41.36% | 3.65M -28.01% | 16.93M -- |
Pretax Income From Continuing Operations | -3.10M -- | -11.83M -- | -10.89M -- | -14.68M -- | -15.99M -415.54% | -21.24M -79.51% | -27.27M -150.32% | -39.97M -172.29% | -33.75M -111.03% | -42.46M -99.88% | -143.44M -- |
Net Income | -3.10M -- | -11.83M -- | -10.89M -- | -14.68M -- | -15.99M -415.54% | -21.24M -79.51% | -27.27M -150.32% | -39.97M -172.29% | -33.75M -111.03% | -42.46M -99.88% | -143.44M -- |
Net Income Attributable to Owners of the Company | -3.10M -- | -11.83M -- | -10.89M -- | -14.68M -- | -15.99M -415.54% | -21.24M -79.51% | -27.27M -150.32% | -39.97M -172.29% | -33.75M -111.03% | -42.46M -99.88% | -143.44M -- |
Preferred Stock Dividends | 3.15M -- | 3.15M -- | 3.12M -- | 4.88M -- | 5.04M +59.98% | 548.00K -82.61% | 0 -100.00% | 0 -100.00% | 0 -100.00% | 0 -100.00% | -- -- |
Net Income Attributable to Common Stockholders | -6.25M -- | -14.98M -- | -14.01M -- | -19.56M -- | -21.03M -236.37% | -21.79M -45.42% | -27.27M -94.65% | -39.97M -104.30% | -33.75M -60.45% | -42.46M -94.86% | -143.44M -- |
Other Comprehensive Income | -19.00K -- | 98.00K -- | -42.00K -- | -34.00K -- | 406.00K +2236.84% | -376.00K -483.67% | 393.00K +1035.71% | -110.00K -223.53% | 235.00K -42.12% | 37.00K +109.84% | 555.00K -- |
Total Comprehensive Income | -3.12M -- | -11.73M -- | -10.94M -- | -14.71M -- | -15.59M -399.39% | -21.62M -84.22% | -26.88M -145.77% | -40.08M -172.40% | -33.51M -115.02% | -42.42M -96.23% | -142.89M -- |
Total Comprehensive Income Attributable to Owners of the Company | -3.12M -- | -11.73M -- | -10.94M -- | -14.71M -- | -15.59M -399.39% | -21.62M -84.22% | -26.88M -145.77% | -40.08M -172.40% | -33.51M -115.02% | -42.42M -96.23% | -142.89M -- |
Basic EPS | -2.11 -- | -- -- | -4.68 -- | -6.5 -- | -6.96 -229.86% | -0.41 -- | -0.51 +89.10% | -0.74 +88.62% | -0.63 +90.95% | -0.78 -90.24% | -2.66 -- |
Basic EPS from Continuing Operations | -2.11 -- | -- -- | -4.68 -- | -6.5 -- | -6.96 -229.86% | -- -- | -0.51 +89.10% | -0.74 +88.62% | -0.63 +90.95% | -- -- | -- -- |
Diluted EPS | -2.11 -- | -- -- | -4.68 -- | -6.5 -- | -6.96 -229.86% | -- -- | -0.51 +89.10% | -0.74 +88.62% | -0.63 +90.95% | -- -- | -- -- |
Diluted EPS from Continuing Operations | -2.11 -- | -- -- | -4.68 -- | -6.5 -- | -6.96 -229.86% | -- -- | -0.51 +89.10% | -0.74 +88.62% | -0.63 +90.95% | -- -- | -- -- |
You can ask Aime
What does Upstream Bio do and what are its main business segments?What guidance did Upstream Bio's management provide for the next earnings period?What is the revenue and EPS growth rate for Upstream Bio year over year?What factors drove the changes in Upstream Bio's revenue and profit?What is Upstream Bio's gross profit margin?What is Upstream Bio's latest dividend and current dividend yield?What is the market's earnings forecast for Upstream Bio next quarter?What were the key takeaways from Upstream Bio’s earnings call?
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