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KPTI

Karyopharm·NASDAQ
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KPTI fundamentals

Karyopharm (KPTI) released its earnings on Nov 3, 2025: revenue was 44.04M (YoY +13.52%), beat estimates; EPS was -3.82 (YoY -1369.23%), missed estimates.
Revenue / YoY
44.04M
+13.52%
EPS / YoY
-3.82
-1369.23%
Report date
Nov 3, 2025
KPTI Earnings Call Summary for Q3,2025
  • Phase III SENTRY Trial Milestone: Enrollment complete, targeting March 2026 readout with 79% SVR35 vs. 35% for ruxolitinib alone.
  • Revenue Growth: Q3 2025 total revenue $44M (+13% YoY), XPOVIO net product revenue $32M (+8.5% YoY).
  • $1B Myelofibrosis Opportunity: 75% physician intent for combination therapy in 4,000 new U.S. patients/year.
  • Financial Flexibility: $100M refinancing extends cash runway to Q2 2026, with no additional sales force needed.
  • Safety Profile: Combination therapy shows 26% Grade 3+ anemia vs. 37% for ruxolitinib, 5-7% discontinuation rate.
EPS
Revenue

Revenue & Expenses

KPTI has released its 2025 Q3 earnings report, with revenue of 44.04M, reflecting a YoY change of 13.57%, and net profit of -33.13M, showing a YoY change of -3.29%. The Sankey diagram below clearly presents KPTI's revenue sources and cost distribution.

Key Indicators

Karyopharm (KPTI) key financial stats and ratios, covering profitability, financial health, and leverage.
Karyopharm (KPTI)'s revenue and profit trends over recent years, visualized with a waterfall chart to showcase the revenue-to-profit funnel.
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Karyopharm (KPTI)'s asset and liability trends over recent years, visualized with a waterfall chart to illustrate changes in its asset-liability structure.
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Karyopharm (KPTI)'s cash flow trends over recent years, visualized with a waterfall chart to illustrate changes in its operating, investing, and financing cash flows.
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Where does Karyopharm (KPTI) generate its revenue? Explore its key revenue streams and top earning regions.
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Track Karyopharm (KPTI) Dividend Yield, Payout Ratio & Sustainability Through Its Dividend History
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