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IONS

Ionis Pharmaceuticals·NASDAQ
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IONS fundamentals

Ionis Pharmaceuticals (IONS) released its earnings on Oct 29, 2025: revenue was 157.00M (YoY +17.16%), beat estimates; EPS was -0.8 (YoY +15.79%), beat estimates.
Revenue / YoY
157.00M
+17.16%
EPS / YoY
-0.8
+15.79%
Report date
Oct 29, 2025
IONS Earnings Call Summary for Q3,2025
  • Revenue Surge: Q3 revenue up 17% YoY to $157M, driven by TRYNGOLZA ($32M Q3 sales) and DAWNZERA launches. 2025 guidance raised to $875-900M.
  • Pipeline Milestones: Olezarsen shows 85% AP reduction in sHTG; zilganersen stabilizes Alexander disease gait speed. Both targeting 2026 launches.
  • Strategic Growth: >$1B peak sales expected for olezarsen; DAWNZERA >$500M. 4 partnered launches by 2027, with $2.1B+ cash for execution.
EPS
Revenue

Revenue & Expenses

IONS has released its 2025 Q3 earnings report, with revenue of 156.72M, reflecting a YoY change of 17.12%, and net profit of -128.61M, showing a YoY change of 8.45%. The Sankey diagram below clearly presents IONS's revenue sources and cost distribution.

Key Indicators

Ionis Pharmaceuticals (IONS) key financial stats and ratios, covering profitability, financial health, and leverage.
Ionis Pharmaceuticals (IONS)'s revenue and profit trends over recent years, visualized with a waterfall chart to showcase the revenue-to-profit funnel.
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Ionis Pharmaceuticals (IONS)'s asset and liability trends over recent years, visualized with a waterfall chart to illustrate changes in its asset-liability structure.
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Ionis Pharmaceuticals (IONS)'s cash flow trends over recent years, visualized with a waterfall chart to illustrate changes in its operating, investing, and financing cash flows.
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Where does Ionis Pharmaceuticals (IONS) generate its revenue? Explore its key revenue streams and top earning regions.
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Track Ionis Pharmaceuticals (IONS) Dividend Yield, Payout Ratio & Sustainability Through Its Dividend History
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