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ALNY

Alnylam Pharmaceuticals·NASDAQ
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ALNY fundamentals

Alnylam Pharmaceuticals (ALNY) released its earnings on Oct 30, 2025: revenue was 1.25B (YoY +149.54%), beat estimates; EPS was 2.9 (YoY +680.00%), beat estimates.
Revenue / YoY
1.25B
+149.54%
EPS / YoY
2.9
+680.00%
Report date
Oct 30, 2025
ALNY Earnings Call Summary for Q3,2025
  • Revenue Growth: Q3 2025 net product revenues up 103% YoY to $851 million, driven by 135% TTR franchise expansion.
  • Guidance Increase: 2025 net product revenue raised to $2.95B-$3.05B (midpoint +10%), reflecting AMVUTTRA ATTR-CM launch strength.
  • U.S. Launch Momentum: AMVUTTRA ATTR-CM Q3 net sales $543 million (+100% QoQ), with 90% U.S. patients within 10 miles of treatment.
  • Pipeline Progress: ZENITH hypertension trial initiated; ALN-6400 Phase II in HHT; MAPT Phase I in Alzheimer's.
  • Financial Discipline: Non-GAAP operating income $476 million (+128% YoY); cash balance $2.7 billion post-refinancing.
EPS
Revenue

Revenue & Expenses

ALNY has released its 2025 Q3 earnings report, with revenue of 1.25B, reflecting a YoY change of 149.35%, and net profit of 251.08M, showing a YoY change of 325.05%. The Sankey diagram below clearly presents ALNY's revenue sources and cost distribution.

Key Indicators

Alnylam Pharmaceuticals (ALNY) key financial stats and ratios, covering profitability, financial health, and leverage.
Alnylam Pharmaceuticals (ALNY)'s revenue and profit trends over recent years, visualized with a waterfall chart to showcase the revenue-to-profit funnel.
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Alnylam Pharmaceuticals (ALNY)'s asset and liability trends over recent years, visualized with a waterfall chart to illustrate changes in its asset-liability structure.
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Alnylam Pharmaceuticals (ALNY)'s cash flow trends over recent years, visualized with a waterfall chart to illustrate changes in its operating, investing, and financing cash flows.
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Where does Alnylam Pharmaceuticals (ALNY) generate its revenue? Explore its key revenue streams and top earning regions.
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Track Alnylam Pharmaceuticals (ALNY) Dividend Yield, Payout Ratio & Sustainability Through Its Dividend History
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