EnVVeno Medical Corporation was incorporated in Delaware on December 22, 1999. The company is a late-stage clinical medical device company focused on the advancement of innovative bioprosthesis solutions to improve the standard of care for the treatment of venous diseases. Chronic venous disease (CVD) is the chronic disease with the highest incidence in the world, affecting about 70% of the adult population in the United States. Chronic venous insufficiency (CVI) is a large subset of CVD. It most often occurs in the valves inside the leg veins, resulting in blood reflux (backflow), calf blood bank, increased venous pressure in the legs (venous hypertension), and in severe cases, non-healing venous ulcers. The company is developing surgical and non-surgical replacement venous valves for patients with severe deep vein system CVI in the leg. 

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