Recorlev market expansion and commercial infrastructure, Gvoke's growth and market strategy, gross margin and
leverage, Recorlev market dynamics and growth potential, Recorlev writers expansion and growth expectations are the key contradictions discussed in
Biopharma's latest 2025Q2 earnings call
Revenue Growth and Commercial Product Portfolio:
-
reported
total revenue of
almost $72 million in Q2 2025, marking a
49% increase, with commercial product portfolio contributing
$68 million, up
46%.
- The growth was driven by increased patient demand across all three products, particularly Recorlev's strong demand and differentiation as a treatment for hypercortisolemia and Cushing's syndrome.
Recorlev's Rapid Growth:
- Recorlev's
revenue grew
136% year-over-year, reaching
over $31 million in Q2 2025, with an average number of patients on therapy increasing by
122%.
- The expansion is attributed to its unique position as a needed treatment and strategic investments in healthcare professional engagement and patient support.
Gvoke Continued Growth:
- Gvoke's
revenue was
$23 million, a
17% increase from Q2 2024, supported by a
5% growth in prescriptions and some gross-to-net favorability.
- Steady prescription volume growth, driven by new and existing prescribers, and increased awareness of medical guidelines, contributed to its consistent performance.
Keveyis' Steady Performance:
- Keveyis'
revenue was
over $11 million in Q2 2025, demonstrating a modest increase in the average number of patients on therapy and growth in new patient starts.
- The performance reflects the strength of the Keveyis brand and the team's focus on execution in treating primary periodic paralysis patients.
Updated Revenue Guidance:
- Xeris raised its full-year 2025 revenue guidance to
$280 million to $290 million, surpassing the previous range of
$260 million to $275 million.
- The revision is based on the strong top-line performance and confidence in the growing demand for commercial products, particularly Recorlev.
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