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Xenon Pharmaceuticals has completed patient recruitment for X-TOLE2, a Phase III clinical trial for azetukalner. The company has also initiated X-NOVA3 for major depressive disorder and X-CEED for bipolar depression. Xenon reported $624.8 million in cash and cash equivalents and marketable securities as of June 30, 2025, which is expected to fund operations into 2027. The appointment of Darren Cline as Chief Commercial Officer is expected to enhance commercial capabilities.

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