Thermo Fisher’s $930M Volume Ranks 107th as 1.68% Drop Reflects Healthcare Sector Volatility

On September 17, 2025, , ranking it 107th among U.S. stocks by dollar volume. , marking a decline from its previous session’s close.

Analysts noted that the drop coincided with broader market volatility driven by shifting investor sentiment toward healthcare sector valuations. While the company’s core diagnostics and life sciences divisions remain resilient, short-term trading dynamics highlighted reduced institutional buying pressure amid macroeconomic uncertainty. The volume-to-price correlation suggests liquidity constraints in the near term, though no material operational updates were disclosed.

Backtesting a strategy based on daily volume rankings reveals a methodological challenge: constructing a synthetic index of the top 500 U.S. stocks by dollar volume requires extensive data aggregation and processing. This approach involves calculating equal-weighted returns for the selected basket each day and chaining these returns into a continuous time series. Alternatively, proxies like high-liquidity ETFs (e.g., SPY or MTUM) offer a simplified but less precise approximation of the strategy’s performance profile.