Tenaya Therapeutics, Inc. declined 2.45% in premarket trading, despite receiving positive safety reviews from independent Data Safety and Monitoring Boards (DSMBs) for its two cardiovascular gene therapy clinical trials, MyPEAK-1 for TN-201 and RIDGE-1 for TN-401. The DSMBs' endorsements allowed the trials to proceed as designed, with enrollment in both dose cohorts of the MyPEAK-1 Phase 1b/2 clinical trial of TN-201 for hypertrophic cardiomyopathy (HCM) complete.
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