Takeda (TAK.US) partners with Keros Therapeutics to develop innovative therapies for blood diseases
Keros Therapeutics today (December 4) announced a global exclusive license agreement with Takeda (TAK.US) to advance the development of elritercept. Elritercept is currently in two Phase 2 clinical trials, one in patients with low-risk or intermediate-risk myelodysplastic syndrome (MDS) and another in patients with myelofibrosis (MF). In addition, the Phase 3 clinical trial RENEW will soon start patient enrollment to evaluate the efficacy of elritercept in adult patients with low-risk or intermediate-risk MDS who are dependent on transfusions. Under the terms of the agreement, Takeda will gain exclusive rights to further develop, manufacture, and commercialize elritercept worldwide (excluding Mainland China, Hong Kong, and Macau). Takeda will take over all development, manufacturing, and commercialization of elritercept as of the effective date of the agreement. Keros will receive a $200 million upfront payment and is eligible to receive over $1.1 billion in development, regulatory, and commercial milestone payments.