Spectral AI shares surge 10.3% after hours on Q4 profit, $18.5M 2026 revenue guidance, and $31.7M BARDA funding.

Spectral AI surged 10.30% in after-hours trading following the release of Q4 2025 financial results and 2026 guidance. The company reported a Q4 net income of $0.6 million, its first profit in the period, and a full-year cash balance of $15.4 million, up from $5.2 million. Key catalysts included a $31.7 million non-dilutive BARDA funding infusion (bringing total contract value to $150 million) and the submission of a De Novo 510(k) application for its DeepView burn system. The 2026 revenue guidance of $18.5 million, driven by ongoing BARDA development work, signaled improved financial discipline and commercialization readiness. These developments reinforced investor confidence in the company’s progress toward FDA approval and long-term growth potential.