Silexion Therapeutics Receives Approval for Phase 2/3 Clinical Trial of SIL204 in Locally Advanced Pancreatic Cancer.

Tuesday, Mar 24, 2026 9:55 am ET1min read
SLXN--

Silexion Therapeutics has received approval from the Israeli Ministry of Health to initiate a Phase 2/3 clinical trial of SIL204 in locally advanced pancreatic cancer. The trial is designed to target KRAS mutations, which are present in over 90% of pancreatic cancers. Positive preclinical results and successful toxicology studies support the trial design. Silexion plans to initiate human clinical trials in Q2 2026.

Silexion Therapeutics Receives Approval for Phase 2/3 Clinical Trial of SIL204 in Locally Advanced Pancreatic Cancer.

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