Silexion Therapeutics' Cancer Drug SIL-204B to Enter Human Trials in Early 2026

Tuesday, Jan 6, 2026 8:25 am ET1min read
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Silexion Therapeutics is developing a cancer drug, SIL-204B, for solid tumor cancers with mutated KRAS oncogene. The drug uses RNA-interference therapeutics and is expected to enter human trials in early 2026. SIL-204B is a locally administered small interfering RNA in an extended-release formulation and is being tested as a first-line treatment for locally advanced pancreatic cancer in combination with standard-of-care chemotherapy.

Silexion Therapeutics' Cancer Drug SIL-204B to Enter Human Trials in Early 2026

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