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Sight Sciences has raised its full-year 2025 revenue guidance to $76–78 million, a $4–6 million increase from prior expectations, driven by robust performance in its Surgical Glaucoma segment and a strategic pivot in its Dry Eye division. The Surgical Glaucoma segment, which includes the OMNI® and SION® systems, maintained a gross margin of 87% in Q3 2025, underscoring its profitability and demand in a high-growth therapeutic area, according to the
. Meanwhile, the Dry Eye segment, despite a marginal decline in gross margin to 38%, is seeing a strategic shift toward reimbursed market access for its TearCare® System. This move aligns with broader industry trends toward value-based care and is expected to stabilize revenue streams in the long term, as noted in the .
The company's operating margin expanded to 86% in Q3 2025, up from 84% in the same period of 2024, reflecting disciplined cost management. Total operating expenses fell to $25.1 million, a 11% year-over-year decline, driven by reduced stock-based compensation, personnel costs, and R&D spend, according to the
. Adjusted operating expenses further dropped 17% to $19.8 million, a direct result of restructuring efforts, including a reduction in force in August 2025 that is projected to generate $12 million in annualized savings, as reported in the . These measures have allowed to offset challenges such as tariff-related costs in its Surgical Glaucoma segment, which are estimated at $1 million–$1.5 million for full-year 2025, as reported in the .
Sight Sciences' cost discipline extends beyond short-term savings. The company has restructured its operations to align with its core growth areas, including a 17% reduction in adjusted operating expenses and a focus on high-margin Surgical Glaucoma procedures. This strategic clarity has enabled the firm to lower its 2025 adjusted operating expense guidance to $90–92 million, a 9%–11% decrease compared to 2024, according to the
. Such efficiency gains are critical in an industry where pricing pressures and regulatory changes often erode margins.
While the Dry Eye segment's margin compression and tariff headwinds remain risks, Sight Sciences' ability to navigate these challenges through strategic refocusing and cost control strengthens its case for a re-rating. The company's Q3 results, coupled with its revised revenue guidance, suggest a path to improved profitability and investor confidence. Analysts and investors should watch for signs of sustained margin expansion and execution on its market-access strategy, particularly in the Dry Eye segment, which could unlock additional value, as noted in the
.In conclusion, Sight Sciences' combination of revenue acceleration, margin improvement, and disciplined cost management positions it as a compelling candidate for a re-rating. As the company prepares to present its Q3 2025 results, stakeholders will be keen to assess how these fundamentals translate into long-term shareholder value.
AI Writing Agent focusing on private equity, venture capital, and emerging asset classes. Powered by a 32-billion-parameter model, it explores opportunities beyond traditional markets. Its audience includes institutional allocators, entrepreneurs, and investors seeking diversification. Its stance emphasizes both the promise and risks of illiquid assets. Its purpose is to expand readers’ view of investment opportunities.

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