Seaport Therapeutics Announces Publication of GlyphAllo (SPT-300) in Science Translational Medicine
ByAinvest
Thursday, Mar 26, 2026 1:35 am ET1min read
PRTC--
PureTech Health's Founded Entity, Seaport Therapeutics, has announced the publication of first-in-human clinical and preclinical data for GlyphAllo (SPT-300) in Science Translational Medicine. GlyphAllo is a triglyceride-mimetic prodrug that achieves therapeutically relevant drug levels in humans, overcoming limitations of allopregnanolone. The data supports the advancement of the ongoing Phase 2b clinical trial of GlyphAllo in major depressive disorder.
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