Rising Health Care Stocks: A Pre-Bell Rally and What It Signals for Long-Term Investors

The healthcare sector in 2025 is at a crossroads, marked by a complex interplay of technological innovation, regulatory shifts, and macroeconomic forces. While the sector has underperformed broader market indices—such as the S&P 500 Health Care Sector Index, which is down 3.1% year-to-date as of July 226 Best Health Care Funds and ETFs for 2025^[1]—the underlying momentum suggests a potential inflection point for long-term investors. This "pre-bell rally," driven by macroeconomic repositioning and sector-specific tailwinds, may signal a strategic entry opportunity for those willing to navigate near-term volatility.

Sector Momentum: From Acute to Non-Acute Care

The healthcare sector is undergoing a structural shift toward non-acute care delivery, with a growing emphasis on digital tools, generative AI, and specialty pharmacy servicesWhat to expect in US healthcare in 2025 and beyond^[2]. According to a report by McKinsey, health services and technology (HST) segments are projected to grow at an 8% compound annual growth rate (CAGR) from 2023 to 2028, fueled by innovations that enhance operational efficiency for payers and providersWhat to expect in US healthcare in 2025 and beyond^[2]. Similarly, specialty pharmacy revenue is expected to rise at a comparable 8% CAGR, driven by the launch of novel therapies and increased patient utilizationWhat to expect in US healthcare in 2025 and beyond^[2].

This transition is not merely a trend but a strategic imperative for healthcare organizations. As Deloitte notes, providers are prioritizing consumer-centric digital platforms to address affordability and access challenges, while cybersecurity investments—now a focus for 60% of health system executives—highlight the sector's evolving risk landscape2025 US health care outlook^[3]. Meanwhile, mergers and acquisitions (M&A) activity is reshaping the industry, with large health systems consolidating outpatient care settings to boost profitability and regional systems streamlining operations amid rising costs2025 US health care outlook^[3].

Macro-Driven Repositioning: Inflation, Policy, and Cost Pressures

The sector's momentum is being tested by macroeconomic headwinds. Healthcare inflation, which hit a three-year high of 4.2% in August 2025CPI report health care inflation rises^[4], is squeezing both providers and consumers. The Consumer Price Index (CPI) rose 2.9% year-over-year in December 2024, outpacing the Health Care Price Index (HCPI) of 2.7%January 2025 Health Sector Economic Indicators Briefs^[5]. This divergence reflects broader economic inflation, with hospital care and dental services seeing price increases of 3.3% and 3.0%, respectively, while prescription drugs lagged at 1.1%January 2025 Health Sector Economic Indicators Briefs^[5].

Policy changes are compounding these pressures. The Inflation Reduction Act (IRA) has introduced financial strain on Medicare Advantage (MA) plans, particularly through caps on out-of-pocket drug costs and expanded low-income subsidiesWhat to expect in US healthcare in 2025 and beyond^[6]. Hospitals, already grappling with underpayments from Medicare and Medicaid—absorbing $130 billion in underpayments in 2023 aloneNew AHA Report: Hospitals and Health Systems Squeezed by …^[7]—face further margin compression as IRA provisions take effect. Meanwhile, the 2025 federal budget reconciliation law's Medicaid work requirements and more frequent eligibility checks are projected to reduce federal spending by billions but may also increase the number of uninsured individualsHealth Provisions in the 2025 Federal Budget Reconciliation Law^[8].

ETF Performance: Undervaluation or Caution?

Healthcare sector ETFs have mirrored the sector's mixed fortunes. The Health Care Select Sector SPDR Fund (XLV) and Vanguard Health Care ETF (VHT) have posted year-to-date returns of -2.41% and -2.44%, respectivelyTop 10 Healthcare ETFs For 2025 | Best Sector Funds To Watch^[9], while the iShares Biotechnology ETF (IBB) has declined more sharply at -13.90%Top 10 Healthcare ETFs For 2025 | Best Sector Funds To Watch^[9]. However, some analysts argue that the sector is undervalued. Janus Henderson's Luyi Guo, for instance, highlights the sector's current 20% discount as an attractive entry point for long-term investors6 Best Health Care Funds and ETFs for 2025^[1].

The Invesco Dorsey Wright Healthcare Momentum ETF (PTH), which tracks high-momentum healthcare stocks, has also faced headwinds due to regulatory scrutiny and global tariff impactsInvesco Dorsey Wright Healthcare Momentum ETF - Markets Insider^[10]. Yet, its focus on technical leaders suggests a potential rebound if macroeconomic conditions stabilize.

Long-Term Implications for Investors

For long-term investors, the healthcare sector's challenges are balanced by its resilience and innovation-driven growth. The shift to non-acute care and digital health platforms offers scalable solutions to persistent issues like affordability and access. Specialty pharmacy and health software segments, in particular, are well-positioned to benefit from demographic trends and therapeutic advancements.

However, risks remain. Regulatory uncertainty, particularly around drug pricing and Medicaid eligibility changes, could disrupt near-term earnings. Additionally, the sector's exposure to inflation—both in labor and supply chain costs—demands careful stock selection. Investors should prioritize companies with strong balance sheets, diversified revenue streams, and a clear digital transformation strategy.

Conclusion

The healthcare sector's "pre-bell rally" reflects a tug-of-war between macroeconomic pressures and structural innovation. While near-term headwinds—ranging from inflation to policy shifts—have dampened ETF performance, the sector's long-term fundamentals remain intact. For investors with a multi-year horizon, the current discount in healthcare stocks may represent a strategic opportunity to capitalize on a sector poised for reinvention. As always, due diligence and a focus on quality will be key to navigating this dynamic landscape.