Rhythm Pharma share sale said to end over 6x oversubscribed

Thursday, Jul 10, 2025 10:54 am ET1min read

Rhythm Pharma share sale said to end over 6x oversubscribed

Shares of Rhythm Pharmaceuticals (RPM) have experienced a significant surge following the company's recent announcement. The biopharmaceutical company's share sale was reported to be over six times oversubscribed, indicating strong investor interest in the company's prospects. The news comes on the heels of positive results from a recent trial of the company's investigational treatment for acquired hypothalamic obesity, a rare form of obesity caused by damage to the hypothalamus.

The Phase 2 trial of bivamelagon, the investigational treatment, achieved statistically significant and clinically meaningful reductions in body mass index (BMI) for patients. This positive outcome suggests that the treatment has the potential to treat patients with acquired hypothalamic obesity and has established an appropriate dose range for future clinical evaluation. The stock price reacted positively to the news, trading 24% higher at $80.86 following Wednesday's opening bell, extending its nearly 80% gain over the past year [1].

David Meeker, the chief executive of Rhythm Pharmaceuticals, expressed optimism about the trial results and the potential for future regulatory alignment. He stated, "We look forward to engaging with U.S. and European regulatory authorities to seek alignment on a Phase 3 trial design as we continue advancing bivamelagon." Meeker also noted that the results of the recent trial were consistent with BMI reductions achieved with setmelanotide therapy in similar patient populations in past trials [1].

The oversubscribed share sale underscores the confidence investors have in Rhythm Pharmaceuticals' pipeline and its potential to address unmet medical needs. The company's focus on rare diseases and its innovative approach to obesity treatment have garnered significant attention and support from the investment community. As Rhythm Pharmaceuticals continues to advance bivamelagon through the clinical trial process, investors will be closely watching the company's progress and regulatory interactions.

References:
[1] https://www.marketwatch.com/story/rhythm-pharma-shares-gain-on-positive-results-from-recent-trial-of-obesity-treatment-46b6bb72

Rhythm Pharma share sale said to end over 6x oversubscribed

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