RBC: Sionna Therapeutics' $2 Billion Valuation is Overly Optimistic

Thursday, Dec 4, 2025 11:48 am ET1min read

Sionna Therapeutics' valuation at over $2 billion is considered too optimistic by RBC. The company is focused on developing novel medicines for cystic fibrosis and is conducting Phase I trials for its NBD1 stabilizers. RBC believes the valuation is too high given the current stage of development and the challenges in the cystic fibrosis treatment market.

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