Radiopharm Theranostics Initiates Phase 1/2a Clinical Trial for BetaBart (RV-01)

Tuesday, Feb 24, 2026 7:32 am ET1min read
RADX--

Radiopharm Theranostics has dosed the first patient in its Phase 1/2a clinical trial of 177Lu-Betabart (RV-01), a Lu177-tagged engineered monoclonal antibody targeting B7-H3. The trial aims to evaluate safety, biodistribution, and radiation dosimetry, as well as preliminary anti-tumor activity. Preclinical studies have shown tumor shrinkage and prolonged survival. The agent was developed by Radiopharm Ventures, a joint venture between Radiopharm and MD Anderson Cancer Center.

Radiopharm Theranostics Initiates Phase 1/2a Clinical Trial for BetaBart (RV-01)

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