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Summary
• Profusa's stock gaps down 18.74% at open, hitting $0.10
• Intraday price plummets 26.3% to $0.0866, nearing 52-week low of $0.082
• Turnover surges 22.89%, signaling liquidity crunch and panic selling
• RSI at 37.66 and MACD at -0.0247 confirm oversold bearish momentum
Profusa (PFSA) has imploded in Monday’s session, joining a broader market wave of gapping stocks. With a 18.74% gap down and a 23.23% intraday decline, the biotech name is now trading near its 52-week low. The move coincides with a mixed sector performance, as Medtronic (MDT) dips 0.23%. Traders are scrambling to decipher whether this is a sector-wide correction or a company-specific crisis.
Bearish Gap and Liquidity Crunch Trigger PFSA’s Freefall
PFSA’s 16.94% selloff is anchored by a 18.74% gap down at open, signaling immediate panic selling. The stock’s 52-week range of $0.09–$12.76 underscores its extreme volatility, while the 13.57% turnover rate suggests a liquidity crunch. No company-specific news directly explains the move, but the broader market’s gap-down stocks list—featuring names like LAZR (-60.06%) and ASTI (-14.42%)—indicates a systemic risk-off environment. Short-term traders are likely unwinding long positions as the RSI (37.66) and MACD (-0.025) confirm bearish momentum.
Biotech Sector Mixed as Amgen (AMGN) Leads Gainers
The biotech sector remains fragmented, with Amgen (AMGN) rising 1.11% despite PFSA’s collapse. Medtronic (MDT) dips 0.23%, reflecting cautious sentiment. While PFSA’s freefall is not directly tied to sector fundamentals, the broader risk-off environment—driven by macroeconomic jitters—has amplified volatility. Investors are pivoting to defensive plays, leaving speculative biotech names like
Short-Term Bearish Setup: Cash-Secured Shorts and ETF Implications
• MACD: -0.0247 (bearish divergence), RSI: 37.66 (oversold), Bollinger Bands: 0.0986–0.2124 (price near lower band)
• 30D MA: 0.1640 (price below), Support: 0.0986 (lower band), Resistance: 0.1555 (middle band)
PFSA’s technicals paint a dire short-term picture. The RSI at 37.66 suggests oversold conditions, but the MACD’s bearish crossover and price action near the Bollinger lower band indicate a continuation of the downtrend. Traders should monitor the 0.0986 support level; a break below could trigger a test of the 52-week low at $0.09. The sector leader Medtronic (MDT) at -0.23% offers limited directional guidance, but its stability contrasts sharply with PFSA’s freefall. With no options available, a cash-secured short position near $0.10 could capitalize on the breakdown, targeting 0.0986 as a stop-loss.
Backtest Profusa Stock Performance
The performance of PFSA (Proxy-Free Short and Long ETF) after a -26% intraday plunge from 2022 to now has been largely negative. The backtest shows a 3-day win rate of 32.88%, a 10-day win rate of 31.51%, and a 30-day win rate of 31.51%, indicating a higher probability of positive returns in the short term compared to the long term. However, the overall returns over the 3, 10, and 30 days were -5.18%, -9.97%, and -19.77%, respectively, with a maximum return of only -2.33% over the 30 days, suggesting that while there were some short-term gains, the overall trend was one of decline.
Act Now: Secure Shorts as PFSA Tests Critical Support
PFSA’s collapse is a textbook short-term bear trap, driven by liquidity exhaustion and broader market jitters. The 0.0986 support level is now in focus; a breach would validate the continuation of the downtrend. Medtronic’s (-0.23%) muted decline suggests the medical device sector isn’t the primary driver here. Investors should prioritize securing short positions near $0.10, with a stop-loss at 0.1555 to mitigate risk. Watch for a breakdown below 0.0986 or a reversal above 0.1555 to dictate next steps. With Amgen (AMGN) rising 1.11%, the sector’s divergence highlights PFSA’s fragility—act decisively to capitalize on this high-conviction short setup.

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