Prime Medicine Reports Full-Year 2025 Financial Results, Plans IND and CTA Submissions, and Advances Clinical Trials for Wilson Disease and AATD Programs.

Tuesday, Mar 3, 2026 8:03 am ET1min read
PRME--

Prime Medicine reported full-year 2025 financial results, with $191M in cash, cash equivalents, and investments, providing a cash runway into 2027. The company plans to file IND and/or CTA for Wilson Disease and AATD programs in 1H 2026 and mid-2026, respectively, with initial clinical data expected in 2027. Ongoing engagement with FDA is underway for PM359 in CGD, with plans to submit a BLA following final alignment.

Prime Medicine Reports Full-Year 2025 Financial Results, Plans IND and CTA Submissions, and Advances Clinical Trials for Wilson Disease and AATD Programs.

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