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Preliminary Data Shows Promising Activity of Petosemtamab in Metastatic Colorectal Cancer
ByAinvest
Saturday, Oct 25, 2025 5:26 am ET1min read
Merus has reported initial interim clinical data for petosemtamab, a bispecific antibody, in combination with FOLFOX/FOLFIRI in 1L, 2L metastatic colorectal cancer (mCRC) and petosemtamab monotherapy in 3L+ mCRC. The data show a 100% response rate in 1L left-sided mCRC and a 62% response rate in 2L left- and right-sided mCRC. The treatment was well-tolerated with good safety profile.
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