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Pfizer (PFE) fell 0.28% on Aug. 18, with a trading volume of $0.90 billion, ranking 84th in market activity. The stock's performance came amid mixed developments affecting its near-term outlook.
Regulatory scrutiny intensified as the FDA requested additional data on a key oncology drug candidate, prompting investor caution. A partnership update with a biotech firm also generated mixed reactions, with analysts noting the agreement's potential to accelerate pipeline development but raising questions about near-term revenue visibility.
Short-term momentum strategies saw limited success in capturing the stock's volatility. A volume-based trading approach involving the top 500 stocks by daily volume yielded a 0.98% average one-day return. Over 365 days, the strategy generated a total return of 31.52%, highlighting the challenges of timing market fluctuations in the pharmaceutical sector.

Market Watch column provides a thorough analysis of stock market fluctuations and expert ratings.

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