Pfizer Announces Positive Phase 2b Results for Obesity Drug with 12.3% Weight Loss

Friday, Feb 6, 2026 12:43 am ET1min read
PFE--

Pfizer announced positive results from its Phase 2b VESPER-3 study of PF-08653944, an injectable GLP-1 receptor agonist for obesity treatment. The trial showed a statistically significant weight loss of up to 12.3% at 28 weeks and a favorable safety profile. Pfizer plans to advance 10 Phase 3 trials in 2026 to address diverse patient needs and comorbidities.

Pfizer Announces Positive Phase 2b Results for Obesity Drug with 12.3% Weight Loss

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