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Summary
• Penumbra’s Q2 revenue surged 13.4% to $339.5M, surpassing estimates by 3.7%
• UBS raised price target to $335, citing double-digit growth visibility and U.S. market share gains
• Intraday price rocketed to $252.94 (up 11.35%), trading at 58.37x dynamic PE, with turnover hitting 1.74%
Penumbra (PEN) has ignited a frenzy on Wall Street, surging 11.86% intraday to $254.09 as of 4:19 PM. This explosive move follows a blockbuster Q2 earnings report, a UBS price target hike to $335, and a robust technical setup. With the stock trading near its 52-week high of $310 and a dynamic PE of 58.64, investors are scrambling to decode whether this is a catalyst-driven breakout or a fleeting surge.
Q2 Earnings and UBS Upgrade Drive Unprecedented Rally
Penumbra’s 11.35% rally was fueled by a blockbuster Q2 earnings report and a bullish UBS upgrade. The company reported $339.5M in revenue (up 13.4% YoY), with U.S. thrombectomy revenue surging 22.6%, driven by CAVT portfolio adoption. Gross margin hit 66%, and operating income of $40.8M (12% of revenue) exceeded expectations. UBS analyst Priya Sachdeva raised the price target to $335 (1.52% increase) and maintained a 'Buy' rating, citing visibility into double-digit growth, low tariff exposure, and market share gains in the U.S. venous thromboembolism (VTE) market. The stock’s sharp move also reflects optimism around the STORM-PE trial, which could redefine treatment standards for pulmonary embolism if positive.
Medical Device Sector Volatility as Penumbra Outperforms Peers
The broader medical device sector showed mixed momentum, with
High-Leverage Options and ETF Plays in a Volatile Setup
• 200D MA: $256.29 (near current price), RSI: 25.69 (oversold), MACD Histogram: +0.036 (bullish divergence)
• Bollinger Band squeeze: $221.47–$254.45; 30D support: $229.86, 200D resistance: $257.06
Top Options:
• PEN20250815C250 (Call): Strike $250, Expiry 8/15, IV 45.91% (high volatility), Leverage 21.99% (amplified gains), Delta 0.567 (moderate sensitivity), Theta -0.625 (rapid time decay), Gamma 0.0157 (price sensitivity)
• PEN20250815C260 (Call): Strike $260, Expiry 8/15, IV 41.18% (moderate volatility), Leverage 42.08% (high amplification), Delta 0.396 (lower sensitivity), Theta -0.494 (moderate decay), Gamma 0.01717 (strong sensitivity)
The C250 and C260 calls offer asymmetric leverage to Penumbra’s near-term breakout potential. The C260’s 42.08% leverage ratio and high gamma (0.01717) suggest it could amplify gains if the stock breaks above $254.45 (upper
Band). With implied volatility in the mid-40s and turnover at 9,098 contracts, liquidity is robust. A 5% upside to $265.59 would yield ~33% return on C250 and 21% on C260, assuming a linear payoff. Aggressive bulls should target $254.45 (Bollinger Band) and $256.29 (200D MA) as critical thresholds.Bullish Momentum Unlikely to Subside—Act Now on High-Leverage Plays
Penumbra’s momentum is underpinned by a rare trifecta of earnings outperformance, analyst upgrades, and favorable technicals. The stock’s 25.69 RSI (oversold) and MACD divergence suggest a continuation of the rally, with the 8/15 options chain offering amplified exposure. Medtronic (MDT), the sector leader, fell 0.24%, underscoring Penumbra’s outperformance. Investors should prioritize the C250 and C260 calls for a 5–7% upside scenario, while monitoring the 200D MA at $256.29 as a key support. With UBS and Wall Street analysts backing the $335–$340 price target, this is a high-conviction trade for those positioned to capitalize on the medical device sector’s next catalyst-driven leader.

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