Penny Stocks on the Move: Today’s Top Gainers and Biggest Decliners

On May 21, 2025, the penny stock market witnessed significant fluctuations, with Lottery.com Inc. emerging as the top gainer with an impressive surge of 131.17%. Conversely, Wolfspeed, Inc. experienced the most substantial decline, plummeting by 59.27%. This dynamic shift highlights the volatile nature of the penny stock market, underscoring both opportunities and risks for investors.

Top Gainers
Lottery.com Inc. (LTRY)
Lottery.com Inc., operating in the Hotels, Restaurants & Leisure industry, experienced a remarkable surge today with its stock price climbing by 131.17%, securing the top rank among penny stocks. The stock reached an intraday high of 1.89 before closing at 1.78 per share. Reports indicate that Lottery.com's recent announcement of achieving compliance with Nasdaq Listing Rules and unveiling ambitious plans for operational expansion across the U.S. by late 2025 have significantly bolstered investor confidence, contributing to today's remarkable stock performance.

SigmaTron International, Inc. (SGMA)
SigmaTron International, Inc., an electronic equipment, instruments, and components manufacturer, saw its stock soar by 130.23% today, marking the second-highest rise in the penny stock market. The stock reached an intraday high of $2.99 and closed at $2.97. Reports indicate that the surge follows the announcement on May 21, 2025, of a merger agreement with Transom Capital Group, where SigmaTron will be acquired for $3.02 per share, a 134% premium over its previous closing price.

Biodesix, Inc. (BDSX)
Biodesix, Inc., a prominent player in the healthcare technology sector, saw its stock surge by 45.76% today, ranking third in the penny stock market. The stock reached an intraday high of $0.515 before closing at $0.395. Reports indicate that Biodesix's revised revenue guidance and strategic sales reconfiguration, announced on May 15, 2025, are key contributors to today's stock surge.

Edible Garden Ag Incorporated (EDBL)
Edible Garden Ag Incorporated, a leader in the food industry, saw a significant stock increase of 38.61% today, ranking fourth among penny stocks. The company's shares reached an intraday high of $6.29, closing at $4.99. Reports indicate that Edible Garden's recent entry into the $103 billion sports nutrition market on May 20, 2025, and the launch of Kick. Sports Nutrition on Amazon, have propelled its stock upward, along with strategic realignment efforts that enhance operational efficiency and margins.

Work Medical Technology Group Ltd (WOK)
Work Medical Technology Group Ltd, a supplier in the medical equipment and supplies industry, experienced a remarkable stock surge of 37.55% today, ranking fifth among penny stocks. It reached an intraday high of $0.95 and closed at $0.696. In recent developments, Work Medical Technology Group Ltd announced a $5 million securities offering pricing on May 20, 2025, and reports indicate its strategic expansion in medical device operations on May 19, 2025, fueling investor optimism.

Top Decliners
Wolfspeed, Inc. (WOLF)
Wolfspeed, Inc., a semiconductor products and equipment provider, saw its stock plummet by a staggering 59.27% today, ranking it first in today's penny stock market for negative movement. The stock reached an intraday low of $0.82 before closing at $1.275. Recent reports indicate that Wolfspeed is preparing to file for bankruptcy within weeks due to overwhelming debt, with post-market trading showing a nearly 60% drop in stock value. The company struggles with weak industrial and automotive market demand alongside tariff-induced uncertainties. Reports from May 20, 2025, highlight its decision to reject several out-of-court debt restructuring proposals, opting instead for a bankruptcy filing supported by most creditors.

Petros Pharmaceuticals, Inc. (PTPI)
Petros Pharmaceuticals, Inc., operating in the pharmaceutical industry, witnessed a significant stock decline of 46.77% today, ranking as the second largest drop in the penny stock market. The stock reached an intraday low of $0.06 and closed at $0.066. Recent reports indicate that Petros Pharmaceuticals received a delisting notice from Nasdaq, prompting a planned appeal. On May 21, 2025, the company announced a 1-for-25 reverse stock split, effective April 30, 2025, in response to non-compliance issues, which analysts say contributed to today's drastic stock decrease.

Urogen Pharma Ltd. (URGN)
Urogen Pharma Ltd. (Nasdaq: URGN), a biopharmaceutical company specializing in pharmaceuticals, saw its stock plummet by 44.70% today, ranking third in the penny stock market for the day in terms of decline. The stock hit an intraday low of $3.42 and closed at $4.17. Recent reports indicate that the company's shares fell sharply after a split decision by an FDA panel on its bladder cancer drug on May 21, 2025. Additionally, on May 21, 2025, analysts say an investigation into UroGen Pharma by a law firm has contributed to the plunge in stock value.

Leddartech Holdings Inc. (LDTC)
Leddartech Holdings Inc., an AI-powered software company, saw its stock plummet by 40.47% today, ranking fourth in market declines among penny stocks. The stock closed at 0.306, slightly above the intraday low of 0.303. Recent reports indicate that on May 20, 2025, LeddarTech announced temporary layoffs of 138 employees, constituting 95% of its workforce, as part of ongoing efforts to secure additional financing amidst discussions with lenders under the Desjardins Credit Facility and Bridge Facility.

Hongli Group Inc. (HLP)
Hongli Group Inc., a machinery manufacturing company, saw its stock plummet by 34.46% today, ranking fifth in declines among penny stocks. The stock hit an intraday low of $0.718 and closed at $0.97. Recent reports indicate that on May 18, 2025, Hongli Group announced a significant drop in full-year earnings, reporting a net loss of $1.88 million compared to a net income the previous year, raising investor concerns and contributing to today's stock decline.