ORIC Pharmaceuticals Presents Positive Enozertinib Data for NSCLC Patients with EGFR Atypical Mutations at ESMO Asia Congress 2025.
ByAinvest
Thursday, Dec 4, 2025 9:45 pm ET1min read
ORIC--
ORIC Pharmaceuticals presented data on enozertinib, a treatment for non-small cell lung cancer (NSCLC) with EGFR atypical mutations, at the ESMO Asia Congress 2025. The trial showed promising results, including an 80% overall response rate and 100% intracranial response rate in first-line patients. Enozertinib also demonstrated a competitive safety profile with manageable on-target toxicity. Enrollment and follow-up continue, with the next update expected mid-2026 ahead of potential Phase 3 trial initiation.

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