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ORIC Pharmaceuticals has announced data from a Phase 1b trial of enozertinib (ORIC-114) at the ESMO Asia Congress 2025. The data showed positive results in previously treated NSCLC patients with EGFR atypical mutations. Preliminary data in 1L NSCLC patients with EGFR P-loop and alpha C-helix compressing (PACC) mutations were also disclosed.
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