Novartis Acquires Pikavation Therapeutics for $2bn, Amidst Patent Cliff Concerns.

Monday, Mar 23, 2026 4:44 pm ET1min read
NVS--

Novartis has acquired Pikavation Therapeutics for $2bn, gaining a pan-mutant-selective PI3Kα inhibitor, SNV4818, for breast cancer and solid tumors. This deal follows Eli Lilly's acquisition of STX-478, another PI3Kα inhibitor. Novartis' stock has dropped nearly 10% on the news, despite the company's optimism about the deal, which aims to improve tolerability and benefit for patients through precision medicine.

Novartis Acquires Pikavation Therapeutics for $2bn, Amidst Patent Cliff Concerns.

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