Mystery Surge Aspire Biopharma Skyrockets 95.71% on 665% Volume Spike Ranks 465th in Market Activity

On October 2, 2025, Aspire Biopharma (ASBP) surged 95.71%, with a trading volume of $250 million—representing a 665.39% increase from the previous day—ranking it 465th in market activity. The sharp rise in liquidity and price movement has drawn attention to the biotech firm’s recent developments, though no additional corporate or regulatory news was disclosed to directly explain the volatility.

Analysts note that the abrupt spike in trading activity may reflect speculative positioning or short-term market sentiment shifts. However, without publicized updates on clinical trials, partnerships, or financial guidance, the driver of the rally remains opaque. Investors are advised to monitor upcoming disclosures for clarity on sustainability.

To run this back-test accurately I need a little more detail about how you’d like the strategy implemented: 1. Universe • Which market / exchange should the “top-500-by-volume” list be drawn from (e.g. all U.S. listed stocks, only NYSE + NASDAQ, a specific index, etc.)? 2. Trade mechanics • Buy at the day’s close and sell at next day’s close – is that acceptable, or would you prefer open-to-close or another convention? 3. Portfolio weighting • Equal-weight across the 500 names, or volume-weighted / market-cap-weighted? 4. Frictions • Should we include estimated transaction costs or slippage, or ignore them? 5. Any other constraints • Minimum price, liquidity filters, etc. Once I have these details I can build the retrieval plan and run the back-test.