MetaVia, Syntekabio collaboration confirms strong inflammatory, cardiometabolic target engagement.
ByAinvest
Wednesday, Feb 4, 2026 8:06 am ET1min read
MTVA--
MetaVia Inc. and Syntekabio Inc. collaborate to develop vanoglipel (DA-1241), an oral G-protein-coupled receptor 119 agonist. AI-based compound-protein interaction modeling using DeepMatcher platform confirms strong target engagement in inflammatory diseases, cardiometabolic disorders, and cancer. This supports the development of vanoglipel for metabolic syndrome associated with hepatic steatosis (MASH) and potential type 2 diabetes treatment.
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