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Merus Reports Promising Petosemtamab Data in Metastatic Colorectal Cancer
ByAinvest
Friday, Oct 24, 2025 10:02 am ET1min read
Merus has reported interim data from a phase 2 trial of petosemtamab in metastatic colorectal cancer. The bispecific antibody demonstrated a 100% response rate in first-line left-sided mCRC and a 62% response rate in second-line left- and right-sided mCRC when combined with standard chemotherapy FOLFOX/FOLFIRI. Petosemtamab monotherapy in third-line and beyond showed a well-tolerated safety profile. The data were presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics.
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