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On August 13, 2025,
(MRK) closed at $82.34, down 0.45% from its previous close, with a trading volume of $0.91 billion, ranking 111th in market activity. The stock had earlier risen 3.00% during regular hours.Merck’s Q2 2025 results showed mixed performance. Revenue fell 1.9% year-over-year to $15.8 billion, driven by a sharp 55% decline in GARDASIL vaccine sales due to weakened demand in China, which reduced overall growth by 9 percentage points. However, non-GAAP earnings per share (EPS) of $2.13 exceeded estimates by $0.10, supported by strong oncology sales. KEYTRUDA revenue grew 9% to $8.0 billion, while animal health and new product launches, including WINREVAIR (cumulative $1 billion in sales), offset some declines.
Management reaffirmed full-year revenue guidance of $64.8 billion and adjusted EPS of $8.92. A $3.0 billion cost-optimization initiative aims to reinvest savings into pipeline development and new product commercialization. Analysts highlighted concerns over GARDASIL’s long-term prospects in China and potential impacts of KEYTRUDA’s patent expiry, though management emphasized diversification and growth from emerging therapies.
The backtest strategy of buying top 500 stocks by daily volume and holding for one day from 2022 to 2025 achieved a 20.15% gain, outperforming passive benchmarks.

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