Merck 0.40 Gain on 170th Ranked 560M Volume Amid China Sales Slump and Global Growth Push
Merck (MRK) closed on August 8, 2025, with a 0.40% gain, trading at $80.59, despite a 35.8% drop in trading volume to $560 million, ranking 170th in market activity. The stock’s performance follows a mixed Q2 earnings report, with revenue declining 2% to $15.8 billion, driven by a $1.3 billion drop in Gardasil sales in China. Excluding China, global growth reached 7%, supported by oncology, animal health, and new product launches like WinRevair and Cavaxib.
Institutional investors increased stakes in MerckMRK-- during Q1 2025, with Mitsubishi UFJMUFG-- Asset Management boosting its position by 11.4% to 4.68 million shares, valued at $420 million. The company also announced a $0.81 quarterly dividend, yielding 4.1% annually, with a payout ratio of 50%. Analysts have mixed ratings, including a price target reduction to $98 by Morgan StanleyMS-- and a “buy” rating from Guggenheim at $115.
Merck’s Q2 earnings call highlighted challenges in China and Japan for Gardasil, with elevated inventories and soft demand. However, KEYTRUDA sales rose 9% to $8 billion, driven by metastatic and early-stage cancer adoption. The company outlined a $3 billion cost-optimization initiative to reinvest in high-growth areas like oncology and cardiopulmonary therapies, including the acquisition of Verona PharmaVRNA-- for COPD treatment. Regulatory milestones, including FDA decisions on subcutaneous pembrolizumab and WinRevair’s PAH label update, are expected in late 2025.
A backtested strategy of purchasing the top 500 stocks by daily trading volume and holding for one day generated a 166.71% return from 2022 to 2025, outperforming the benchmark by 137.53%. High-volume days, such as August 1, 2025, saw significant gains in stocks like NewmontNEM-- and McKessonMCK--, underscoring liquidity concentration’s role in short-term performance. While the strategy highlights momentum opportunities in volatile markets, risks include volatility and dependence on sustained liquidity.

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