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Medtronic's decision to spin off its Diabetes business—a move expected to unlock significant value for shareholders—represents a strategic inflection point for the medical device giant. By separating its 8%-revenue-generating diabetes division into a standalone entity,
aims to capitalize on two distinct growth engines: a streamlined core business focused on high-margin technologies and a specialized diabetes company poised to dominate the automated insulin delivery (AID) market. For investors, this bifurcation offers a compelling opportunity to participate in both a reinvigorated Medtronic and a high-growth diabetes entity, all while benefiting from margin accretion and sector catalysts.The Diabetes division, which contributed $2.7 billion in revenue in fiscal 2025 (8% of Medtronic's total), will emerge as a standalone company through an IPO followed by a split-off. This separation is designed to be tax-free for shareholders and is expected to be immediately accretive to Medtronic's adjusted EPS, with margin improvements of 50 basis points in gross margin and 100 basis points in operating margin. The new entity will focus on its industry-leading AID systems, including the MiniMed™ 780G insulin pump and Simplera Sync™ continuous glucose monitor (CGM), which together form a complete ecosystem for intensive insulin delivery.

The spin-off also enables Medtronic to shed lower-margin diabetes operations while retaining its core franchises in cardiovascular, neuroscience, and surgical technologies. The new diabetes company, led by CEO Que Dallara, will have the agility to innovate in markets like Smart MDI (multi-dose insulin) and digital health solutions, unburdened by Medtronic's broader portfolio.
Post-separation, Medtronic's core business will focus on high-margin, high-growth technologies such as:
1. Pulsed Field Ablation (PFA): A minimally invasive heart rhythm therapy with a 30%+ global market adoption rate.
2. Renal Denervation: A procedure to treat hypertension, now supported by positive late-stage trial data.
3. Soft Tissue Robotics: Surgical robotics for complex procedures, a segment growing at ~15% annually.
These areas already drive Medtronic's mid-single-digit organic revenue growth, with fiscal 2025 results showing a 4.9% organic revenue increase to $33.5 billion and non-GAAP EPS of $5.49 (+6% year-over-year). The spin-off's margin accretion will further strengthen profitability, while freeing capital for share buybacks and R&D.
Medtronic's stock trades at a 15.5x forward P/E, below its five-year average of 17.8x and lower than peers like
(ABT: 22.3x) and Johnson & Johnson (JNJ: 21.4x). This discount reflects market skepticism about its diabetes division's drag on margins and growth. However, the spin-off's accretive effects—combined with the core business's focus on high-margin innovation—could narrow this gap.The impending separation also creates a “catalyst window” for revaluation. Historically, spin-offs like Abbott's separation of AbbVie (2013) and Cigna's spin from Express Scripts (2018) delivered shareholder returns exceeding 40% in the 12 months following announcement. For Medtronic, the 18-month timeline to completion (targeting late 2026) creates a clear timeline for investors to capitalize on the undervalued opportunity.
Medtronic's spin-off is a masterstroke of capital allocation, transforming a mixed portfolio into two focused, high-margin entities. With the diabetes division gaining independence to accelerate innovation and the core business sharpening its focus on high-growth markets, investors are positioned to benefit from margin expansion, EPS accretion, and sector tailwinds.
Investment Advice:
- Buy Medtronic (MDT) at current levels (~$105/share) for a 6–12-month horizon, targeting a 20x P/E multiple post-spin-off.
- Monitor: .
- Catalysts: Positive PFA/renal denervation trial data, FDA approvals, and progress toward the 2026 separation.
The separation is a rare “value-creation event” in a stagnant healthcare sector. Act now to capture the upside before the market prices in the benefits.
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