McKessons Volume Slumps to 318th in U.S. as Strategic Shifts and Surpassing S&P 500 Strategy Attract Attention

McKesson (MCK) closed on September 10, 2025, , , ranking it 318th among U.S. stocks by activity. The move followed a strategic reassessment of its distribution network and regulatory updates in pharmacy benefit management (PBM) services, which influenced investor sentiment in the sector.

The stock’s muted volume was attributed to reduced speculative activity as institutional investors shifted focus to earnings-driven equities. Analysts noted that McKesson’s recent operational adjustments, including cost optimization initiatives, have stabilized its long-term growth trajectory, though short-term volatility remains tied to macroeconomic indicators.

, . The strategy, which rebalanced daily by selecting top-500 volume stocks, . , reflecting high liquidity in the tested universe.