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On August 11, 2025,
(MCK) traded with a volume of $560 million, a 35.05% decline from the previous day, ranking 172nd in market activity. The stock closed up 0.63% amid mixed institutional and insider activity.Citigroup Inc. significantly increased its stake in McKesson during Q1, boosting holdings by 107.8% to 140,058 shares valued at $94.26 million. Other institutional investors, including T. Rowe Price and
, also raised positions, with GAMMA Investing LLC adding 2.39 million shares in the first quarter. However, insiders sold shares, including EVP Leann B. Smith and CFO Britt J. Vitalone, reducing their holdings by 32.26% and 30.03%, respectively, totaling $37.24 million in insider sales over 90 days.Analyst optimism remained strong, with
raising its price target to $800 and maintaining a "buy" rating. and Cowen also reiterated positive outlooks, while ISI and adjusted targets upward. Despite a recent EPS miss of $0.07, McKesson reported $97.83 billion in quarterly revenue, exceeding estimates. The company also announced a quarterly dividend increase to $0.82 per share, up from $0.71, reflecting a 15.5% year-over-year hike.The strategy of purchasing the top 500 stocks by daily trading volume and holding them for one day delivered a 166.71% return from 2022 to the present, outperforming the benchmark by 137.53%. This highlights the role of liquidity concentration in short-term performance, particularly in volatile markets. The approach showed notable results in stocks like McKesson, which saw a 0.76% gain on August 1, 2025, aligning with the strategy’s principles.

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