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On August 21, 2025,
(MCK) closed with a 0.44% rise, trading on a volume of $540 million—down 27.18% from the previous day’s activity and ranking 146th in market share among listed equities. The giant operates through four core segments: U.S. Pharmaceutical, Prescription Technology Solutions (RxTS), Medical-Surgical Solutions, and International. Its U.S. Pharmaceutical division distributes a broad range of pharmaceutical products while offering clinical and operational support to specialty practices. The RxTS segment focuses on bridging patients, pharmacies, and biopharma partners to enhance medication accessibility and affordability. The Medical-Surgical Solutions unit delivers logistics and biomedical services to healthcare providers, while the International segment extends its reach through global distribution networks.McKesson’s business model reflects a diversified approach to healthcare supply chains, with operations spanning drug distribution, technology integration, and international logistics. Founded in 1833, the Irving, Texas-based firm has maintained a strategic focus on addressing systemic challenges in patient care through its cross-sector partnerships. Recent trading activity suggests limited short-term volatility, though the sharp decline in daily trading volume indicates reduced immediate market interest compared to prior sessions.
The backtested strategy of purchasing the top 500 stocks by daily trading volume and holding for one day from 2022 to present yielded a compound annual growth rate of 6.98%. However, the approach experienced a maximum drawdown of 15.59% during the testing period, with a notable downturn recorded in mid-2023. This underscores the necessity of risk mitigation measures even in strategies appearing to offer consistent returns.

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