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Mayne Pharma shares plummeted 30% after US-based Cosette Pharmaceuticals initiated a review of their $432.1 million acquisition deal due to a "material adverse change" in Mayne's business and finances. Cosette cited Mayne's trading performance, legal case with TherapeuticsMD, and FDA talks as the reasons for the review. Mayne rejected the issues raised and remains open to talks to resolve the matter.

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