Lilly's (LLY.US) new blockbuster drug "tirzepatide" has filed its fifth NDA in China
On December 14, the latest public information on the website of the National Medical Products Administration's Drug Review Center (CDE) showed that Eli Lilly's (LLY.US) blockbuster drug tirzepatide, a dual agonist of GIP/GLP-1 receptors, has been accepted for a new indication application. The specific indication has not been disclosed. According to the CDE's website, this is the fifth submission of tirzepatide for marketing authorization in China, of which two have been approved by the NMPA previously.Tirzepatide is a weekly injectable drug that activates both the glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. Currently, Eli Lilly is also continuously exploring the application of tirzepatide in various indications.According to Eli Lilly's pipeline information on its website, tirzepatide is also in phase 3 clinical trials for multiple indications, including reducing the incidence and mortality of obesity and reducing adverse cardiovascular outcomes in patients with type 2 diabetes.