LatchBio Releases a 25 Million Cell Human Spatial Transcriptomics Atlas and AI-Driven Curation Tools

LatchBio has released a 25 million cell human spatial transcriptomics atlas, covering 45 tissue types, 63 diseases, and 11 spatial technologies. The atlas is the largest open-source human spatial atlas to date. LatchBio also developed an agentic spatial curation toolkit, which improves per-dataset curation times by 40x and boosts annotation quality and consistency. The company is offering a white-labeled platform for solution providers to build and distribute data portals.

San Francisco, September 02, 2025 — LatchBio, a leading provider of white-labeled data infrastructure, analysis tools, and delivery portals for scientific research, has released a groundbreaking 25 million cell human spatial transcriptomics atlas. This comprehensive dataset spans 11 spatial technologies, including 10X Genomics Visium, Visium HD, Xenium, Bruker Spatial CosMx, STOmics Stereo-seq, Vizgen MERSCOPE, Takara Bio Seeker, AtlasXOmics DBiT-seq, Spatial Genomics GenePS (seqFISH), Element Biosciences AVITI24, and Singular Genomics G4X [1].

The atlas covers an extensive range of 45 tissue types, 63 diseases, and is the largest open-source human spatial atlas to date. It is accessible via a public-facing portal at console.latch.bio/data-portal, enabling scientists to analyze and utilize the data for various research purposes [1].

LatchBio's release is part of a broader trend in engineering biology towards data-driven discovery. The company's CTO, Kenny Workman, emphasizes the importance of large volumes of high-quality spatial measurements in training models and building atlases, stating that these measurements are essential for AI labs and data-driven translational teams to explore new hypothesis spaces [1].

To facilitate the analysis of this vast dataset, LatchBio has developed an agentic spatial curation toolkit. This toolkit improves per-dataset curation times by approximately 40x and enhances annotation quality and consistency by incorporating information from entire papers and unstructured supplements. Each dataset is published on the portal as an annotated H5AD, structured with standardized ontologies for assay, cell type, condition, disease, tissue, patient ID, and organism [1].

LatchBio's white-labeled platform is designed to assist solution providers in building and distributing data portals. These portals are bundled with their kits and help scientific customers answer their questions more efficiently. AtlasXOmics, one of the companies collaborating with LatchBio, highlights the platform's ability to significantly reduce the time required to process raw data into publication-ready figures, from months to days [1].

The company is encouraging solution providers to contribute new datasets to the atlas or to set up their own white-labeled portals to decrease repurchasing cycles. Interested parties can contact LatchBio at alfredo@latch.bio for more information [1].

References:
[1] https://www.businesswire.com/news/home/20250905090341/en/LatchBio-Releases-a-25-Million-Cell-Human-Spatial-Transcriptomics-Atlas-and-Agentic-Spatial-Curation-Tools