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Lantheus Q3 2024: Blockbuster Performance, Strategic Growth

Victor HaleThursday, Nov 7, 2024 2:11 am ET
1min read
Lantheus Holdings Inc. (LNTH) reported strong financial results for the third quarter of 2024, driven by robust sales growth and strategic investments. The company's flagship diagnostic agent, PYLARIFY, maintained its blockbuster status, with sales on track to exceed $1 billion in 2024. Lantheus' commitment to operational excellence, financial discipline, and prudent capital deployment has positioned the company for continued growth and shareholder value.


Lantheus' worldwide revenue increased 18.4% year-over-year to $378.7 million in Q3 2024. This growth was fueled by a 20.6% increase in PYLARIFY sales, driven by strategic partnerships and increasing volumes at existing accounts. Additionally, DEFINITY sales grew 14.3% due to market growth and opportunistic sales stemming from competitor supply challenges.


The company's adjusted fully diluted earnings per share (EPS) increased 15.6% to $1.70, reflecting its strong financial performance. Lantheus' cash and cash equivalents grew to $866.4 million, even after accounting for strategic investments and milestone payments. The company's solid balance sheet and cash flow generation demonstrate its financial stability and commitment to growth.

Lantheus' radiopharmaceutical pipeline progress is another key driver of its success. The company expanded its Alzheimer's disease portfolio with the acquisition of NAV-4694, a novel beta-amyloid imaging agent in Phase 3 clinical development. This acquisition complements Lantheus' existing tau radiodiagnostic, MK-6240, and positions the company to submit New Drug Applications for both agents in 2025 and 2026, respectively.


The SPLASH Phase 3 registrational study of PNT2002, an investigational PSMA-targeted radiotherapeutic for metastatic castration-resistant prostate cancer, met its primary endpoint of radiographic progression-free survival (rPFS). The study's second interim analysis confirmed the meaningful and statistically significant improvement of the PNT2002 arm compared to the alternate androgen receptor pathway inhibitor (ARPI) or hormone therapy.

Lantheus' strategic focus on radiopharmaceuticals, operational excellence, and financial discipline has enabled the company to maintain its market leadership and drive growth. With a strong balance sheet, robust cash flow, and a promising pipeline, Lantheus is well-positioned to continue delivering value to shareholders. As the company expands its portfolio of late-stage and high-potential early-stage product candidates, investors can expect Lantheus to remain a compelling opportunity in the radiopharmaceutical sector.
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