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Karyopharm Therapeutics' consensus analyst price target has decreased from $15.67 to $14.67, reflecting cautious sentiment. Analysts highlight solid Xpovio sales, reduced financial overhangs, and key milestone timelines. However, concerns around valuation and capital needs remain. The company reaffirmed its 2025 earnings guidance, completed enrollment in the SENTRY trial, and executed financial transactions to support operations and research.

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