iSpecimen 2025 Q3 Earnings Net Loss Widens 93.1% Despite EPS Improvement
iSpecimen (ISPC) reported fiscal 2025 Q3 earnings on November 17, 2025, showing a 77.1% improvement in per-share losses but a 93.1% increase in net loss. The results highlight persistent financial challenges despite cost-cutting measures.
Revenue
The company’s total revenue declined sharply to $106,592 in Q3 2025, a 96.0% drop from $2.66 million in the prior-year period. Specimens contracts with customers accounted for the lion’s share of revenue at $95,816, with shipping and other services contributing an additional $10,776. The segment breakdown underscores a reliance on core specimen contracts as ancillary revenue streams contracted.


Earnings/Net Income
iSpecimen narrowed its per-share loss to $0.48 in Q3 2025 from $2.10 in Q3 2024, reflecting a 77.1% improvement. However, the company’s net loss widened to $2.78 million, a 93.1% increase from $1.44 million in the prior-year quarter. The EPS improvement is positive, but the widened net loss indicates ongoing financial challenges.
Price Action
ISPC’s stock price plummeted 28.19% month-to-date as of November 17, 2025, following a 9.91% decline during the preceding full trading week. The latest trading day saw a 7.89% drop, reflecting investor concern over the company’s financial outlook.
Post-Earnings Price Action Review
The strategy of buying iSpecimenISPC-- shares on the date of its earnings release and holding for 30 days has shown poor performance over the past three years. The average return per trade is -6.59% over 12 months, with a 71% success rate, indicating significant underperformance compared to the market. While the 3-month average return is slightly better at +11.61%, the overall trend remains a challenging risk-return profile.
Additional News
Recent filings and news underscore iSpecimen’s liquidity concerns. For the nine months ended September 30, 2025, revenue fell 76% year-over-year to $1.88 million, with a net loss of $5.49 million. Cost reductions and equity financings improved short-term liquidity, but substantial doubt persists about the company’s ability to continue as a going concern. These developments highlight ongoing operational and financial risks, including potential insolvency.
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