Ionis Pharmaceuticals Raises 2025 Revenue Guidance to $900M Amid Accelerated TRYNGOLZA and DAWNZERA Launches

Wednesday, Oct 29, 2025 6:29 pm ET1min read
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Ionis Pharmaceuticals has raised its 2025 revenue guidance to $900M, driven by the acceleration of launches for TRYNGOLZA and DAWNZERA. CEO Brett Monia highlighted the third quarter as a "watershed moment" for the company, citing progress in advancing first and best-in-class medicines for serious diseases. The guidance increase reflects strong momentum in Ionis' core focus areas.

Ionis Pharmaceuticals Raises 2025 Revenue Guidance to $900M Amid Accelerated TRYNGOLZA and DAWNZERA Launches

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