Intuitive Surgical's $1B Volume Ranks 76th Amid Regulatory Uncertainty and Market Reassessment

On September 12, 2025, , ranking 76th among stocks in terms of liquidity. , reflecting market sentiment shifts amid broader sector dynamics.

Analysts observed heightened sensitivity to recent regulatory developments in the robotic surgery space, with investors reassessing long-term growth prospects. A pending FDA review of next-generation surgical systems has sparked technical discussions about potential market share reallocation, though no direct product disruptions were announced.

Short-term show mixed signals, with volume contraction contrasting against sustained institutional positioning. The stock's performance remains anchored to its core business fundamentals, including procedure volume trends and international adoption rates, which remain undisclosed in recent filings.

To run this back-test accurately I need to pin down a few practical details: 1. Market universe – do you want the entire U.S. stock market (all listed common stocks), or another universe (e.g., only the S&P 500 constituents, only NASDAQ-listed shares, a specific country, etc.)? 2. Entry / exit prices – should I assume: • Buy at the day’s open and sell at the same day’s close, or • Buy at the prior close and sell at the next close? (Your wording suggests “buy at the open, hold for one trading day, sell at that day’s close,” but I’d like to confirm.) 3. Weighting scheme – equal-weight each of the top-500 names, correct? 4. Transaction costs or slippage – include any, or ignore them? Once I have those four points confirmed I can generate the daily signal set (top-500 by dollar volume ranked each morning) and run the performance attribution from 2022-01-03 through today.