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Insmed (INSM) closed at $127.05 on 2025-08-19, down 0.05% with a trading volume of $270 million, marking a 39.6% decline from the prior day's volume. The stock ranked 381st in trading activity for the session. A Form 144 filing revealed an insider planned to sell 25,000 shares via Merrill Lynch, valued at $3.19 million, sourced from stock plan awards between 2020 and 2025. The proposed sale constitutes 0.012% of outstanding shares, with the seller attesting to no undisclosed material adverse information.
Recent institutional activity included a $1.19 million open-market sale of 12,546 shares in June 2025. Analyst coverage remained mixed, with
Fitzgerald maintaining an "Overweight" rating and reaffirming a "Buy." Institutional investors, including Long Focus Capital and Suvretta Capital, adjusted holdings in the stock. The insider's prior transactions suggest ongoing liquidity management, though the scale of sales is relatively minor relative to total shares outstanding.The strategy of buying the top 500 stocks by daily trading volume and holding them for one day from 2022 to 2025 yielded a 1-day return of 0.98% and a total return of 31.52% over 365 days. This highlights the potential for capturing short-term momentum while reflecting inherent market volatility and timing risks.

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