IDEXX Shares Drop 2.94% Amid $410M Surge in Volume Slides to 314th in Liquidity Rank
IDEXX Laboratories (IDXX) closed on October 1, 2025, with a 2.94% decline, despite a 73.71% surge in trading volume to $410 million, ranking it 314th in market liquidity. The stock’s performance followed mixed market sentiment amid sector-specific dynamics.
Recent developments highlight the company’s strategic challenges. A pending regulatory review of its diagnostic product portfolio has introduced near-term uncertainty, while a key partnership renewal with a veterinary software provider added limited upside. Analyst commentary remains split, with some emphasizing long-term growth potential in companion animal health but others cautioning about margin pressures from competitive pricing in the livestock diagnostics segment.
Market participants are closely monitoring capital allocation decisions, as the firm announced a revised share repurchase authorization. While the move signals management confidence, its impact on earnings per share remains speculative without concrete execution timelines. Technical indicators show the stock has tested key support levels, raising questions about short-term stability.
To execute this back-test accurately I need a bit more detail about the universe and signal construction, because “top 500 stocks by daily trading volume” can be defined in several ways: 1. Universe • All U.S. listed common stocks? • Only S&P 500 constituents? • Another universe? 2. Volume metric • Dollar volume = Price × Shares traded? • Raw share volume? 3. Re-balancing mechanics • Buy at today’s close, sell at tomorrow’s close (i.e., use “close” prices for both legs)? • Equal-weight the 500 names each day, with full turnover daily (i.e., re-rank every day)? 4. Risk controls (if any) • Stop-loss / take-profit limits, maximum drawdown cap, etc. 5. Transaction costs • Should we include an estimated commission/slippage per trade or assume zero? Once we nail these down I can generate the daily signals file and run the strategy back-test from 2022-01-03 (first trading day of 2022) to the latest available data. Let me know your preferences and I’ll proceed.

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