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Several healthcare and life sciences companies posted significant gains in after-hours trading, driven by clinical updates and earnings releases. Tectonic Therapeutic Inc. (TECX) surged 30.93% after positive topline results from its Phase 1b Part B trial, while Glaukos Corp. (GKOS) advanced 15.45% after reporting third-quarter net sales of $133.5 million. Guardant Health Inc. (GH) gained 19.29% with third-quarter revenue of $265.2 million, and Align Technology, Inc. (ALGN) saw its shares jump 15.15% after posting third-quarter net income of $56.8 million. Neumora Therapeutics, Inc. (NMRA) also made a strong move, climbing 23.20% despite no accompanying news.

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